P9703-50MG Display Image

Pimaricin, from Streptomyces chattanoogensis, >=95% (HPLC)

Code: P9703-50MG D2-231

Application

Pimaricin is an amphoteric antibiotic from Streptomyces chattanoogensis. It is used for a variety of fungal infections, mainly topically. It is used as a...

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£412.00 50MG
List Price

Application

Pimaricin is an amphoteric antibiotic from Streptomyces chattanoogensis. It is used for a variety of fungal infections, mainly topically. It is used as an ergosterol and cholesterol binding agent to study lipid bilayer dynamics, especially in fungal cells. Pimaricin is used as a fungicide in agar media. It is used to study the pleitropic regulator AdpAch and the gamma-butyrolactone regulatory system of Streptomyces chattanoogensis.

Biochem/physiol Actions

An antifungal polyene macrolide that binds specifically to ergosterol and blocks fungal growth. However, unlike nysatin and filipin, pimaricin does not change the permeability of the plasma membrane

General description

Chemical structure: macrolide

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8 °C. Light sensitive.

Packaging

50, 100 mg in glass bottle

25 mg in poly bottle

antibiotic activity spectrumfungi
Quality Level300
InChI keyNCXMLFZGDNKEPB-FFPOYIOWSA-N
biological sourceStreptomyces chattanoogensis
storage temp.2-8°C
assay≥95% (HPLC)
solubility0.1% formic acid in methanol: soluble 1 mg/mL
Mode of actioncell membrane | interferes
SMILES stringC[C@@H]1CC=CC=CC=CC=C[C@@H](C[C@@H]2O[C@](O)(C[C@@H](O)C[C@H]3O[C@@H]3C=CC(=O)O1)C[C@H](O)[C@H]2C(O)=O)O[C@@H]4O[C@H](C)[C@@H](O)[C@H](N)[C@@H]4O
Featured IndustryAgriculture
formpowder
formlyophilized powder
InChI1S/C33H47NO13/c1-18-10-8-6-4-3-5-7-9-11-21(45-32-30(39)28(34)29(38)19(2)44-32)15-25-27(31(40)41)22(36)17-33(42,47-25)16-20(35)14-24-23(46-24)12-13-26(37)43-18/h3-9,11-13,18-25,27-30,32,35-36,38-39,42H,10,14-17,34H2,1-2H3,(H,40,41)/b4-3+,7-5+,8-6+,11-9+,13-12+/t18-,19-,20+,21+,22+,23-,24-,25+,27-,28+,29-,30+,32+,33-/m1/s1

Code
Description
Unit Size
List Price
Qty
P9703-100MG
Unit:100MG
List Price: £718.00
Source:List Price
ADD
P9703-25MG
Unit:25MG
List Price: £238.00
Source:List Price
ADD
Cas Number7681-93-8