SAB1404882-100UG Display Image

Monoclonal Anti-STIP1, (C-terminal) antibody produced in mouse, clone 1E3, purified immunoglobulin, buffered aqueous solution

Code: SAB1404882-100UG D2-231

General description

STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It i...

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£371.00 100UG
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General description

STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM

Immunogen

STIP1 (NP_006810.1, 445 a.a. ~ 543 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequenceTKAMDVYQKALDLDSSCKEAADGYQRCMMAQYNRHDSPEDVKRRAMADPEVQQIMSDPAMRLILEQMQKDPQALSEHLKNPVIAQKIQKLMDVGLIAIR

Physical form

Solution in phosphate buffered saline, pH 7.4

shipped indry ice
isotypeIgG2aκ
antibody formpurified immunoglobulin
application(s)indirect ELISA: suitable
application(s)immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
application(s)western blot: 1-5 µg/mL
application(s)capture ELISA: suitable
application(s)indirect immunofluorescence: suitable
NCBI accession no.NM_006819
storage temp.−20°C
Quality Level100
mol wtantigen ~37 kDa
antibody product typeprimary antibodies
conjugateunconjugated
UniProt accession no.P31948
biological sourcemouse
Gene Informationhuman ... STIP1(10963)
species reactivitymouse, rat, human
formbuffered aqueous solution
clone1E3, monoclonal