SAB1404877-200UL Display Image

Monoclonal Anti-EDAR antibody produced in mouse, clone 3A7, ascites fluid, buffered aqueous solution

Code: SAB1404877-200UL D2-231

General description

This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodyspla...

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£371.00 200UL
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General description

This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. (provided by RefSeq)

Immunogen

EDAR (NP_071731, 64 a.a. ~ 178 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequenceTKDEDYGCVPCPAEKFSKGGYQICRRHKDCEGFFRATVLTPGDMENDAECGPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTKECVGATSGASANFPGTSGSSTLSPFQHAHKEL

Physical form

Clear solution

Gene Informationhuman ... EDAR(10913)
clone3A7, monoclonal
UniProt accession no.Q9UNE0
shipped indry ice
application(s)indirect ELISA: suitable
application(s)western blot: 1:500-1:1000
antibody formascites fluid
NCBI accession no.NM_022336
storage temp.−20°C
Quality Level100
antibody product typeprimary antibodies
isotypeIgG2bκ
mol wtantigen ~38.76 kDa
conjugateunconjugated
biological sourcemouse
species reactivityhuman