SML1071-25MG Display Image

ML240

Code: SML1071-25MG D2-231

Application

ML240 has been used as an inhibitor of D2 ATPase activity of valosin-containing protein.

Biochem/physiol Actions

ML240 is a selective...


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Your Price
£372.00 25MG
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Application

ML240 has been used as an inhibitor of D2 ATPase activity of valosin-containing protein.

Biochem/physiol Actions

ML240 is a selective, ATP-competetive inhibitor of AAA ATPase p97, also called valosine containing protein (VCP). The IC50 for p97 inhibition is 110 nM. ML240 rapidly induces activity of Caspases 3 and 7, leading to apoptosis. ML240 has potent antiproliferative activity towards NCI-60 cancer cell lines.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
color, white to yellow to light brown
formpowder
InChI keyNHAMBLRUUJAFOY-UHFFFAOYSA-N
InChI1S/C23H20N6O/c1-30-19-13-7-10-16-20(19)27-23(28-21(16)25-14-15-8-3-2-4-9-15)29-18-12-6-5-11-17(18)26-22(29)24/h2-13H,14H2,1H3,(H2,24,26)(H,25,27,28)
Quality Level100
SMILES stringNC1=NC2=C(C=CC=C2)N1C3=NC4=C(OC)C=CC=C4C(NCC5=CC=CC=C5)=N3
solubilityDMSO: 5 mg/mL, clear (warmed)
storage temp.2-8°C
Code
Description
Unit Size
List Price
Qty
SML1071-5MG
ML240

Unit:5MG
List Price: £119.00
Source:List Price
ADD
Cas Number1346527-98-7
This product has met the following criteria: