Butyl Sepharose 4 Fast Flow is a well established, standard aliphatic hydrophobic interaction chromatography (HIC) resin for capture and intermediate purification of larger proteins.
- Standard aliphatic HIC resins based on Sepharose Fast Flow base matrix derivatized via uncharged, chemically-stable ether linkages.
- Optimized for the separation of larger proteins in capture and intermediate purification steps
- BioProcess resin supported for industrial applications and well-established in approved processes
- The hydrophilic nature of the base matrix ensures low levels of non-specific binding.
Butyl Sepharose 4 Fast Flow is part of the Sepharose Fast Flow HIC platform, which has been an industrial standard for HIC chromatography during recent decades. Butyl Sepharose 4 Fast Flow is based on cross-linked 4% agarose. The aliphatic ligand is immobilized to the base matrix with an ether linkage. The ligand contains no charged groups, making true hydrophobic interaction chromatography possible, without interfering ionic effects.
Butyl Sepharose 4 Fast Flow is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess resins range, Butyl Sepharose 4 Fast Flow meets industrial demands with security of supply and comprehensive technical and regulatory support