UHPLC Analysis of Proteins on BIOshell™ A160 Peptide C18 2.7 µm; BIOshell™ A400 Protein C18, 3.4 µm; and BIOshell™ IgG 1000 Å C18, 2.7 µm
BIOshell™ 400 Å Protein C18 columns contain 3.4 µm advanced Fused-Core® particles with 400 Å pores that are specifically engineered to provide efficient separation of larger proteins. These columns offer maximum hydrophobicity for resolving tricky hydrophilic and PEGylated proteins. The 3.4 µm Fused-Core particles allow a shorter analysis time yet similar back pressure to fully porous 1.7 µm, 300 Å fully porous C18 particles. These columns can be operated long term at pressures up to 9000 psi (600 bar), temperatures up to 90 °C, and within the pH range of 1 to 9.
BIOshell is a trademark of Sigma-Aldrich Co. LLC
Fused-Core is a registered trademark of Advanced Materials Technology, Inc.
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