SAB1406463-50UG Display Image

Anti-SNX1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution

Code: SAB1406463-50UG D2-231

General description

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and...

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General description

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. (provided by RefSeq)

Immunogen

SNX1 (AAH00357.1, 1 a.a. ~ 522 a.a) full-length human protein.SequenceMASGGGGCSASERLPPPFPGLEPESEGAAGGSEPEAGDSDTEGEDIFTGAAVVSKHQSPKITTSLLPINNGSKENGIHEEQDQEPQDLFADATVELSLDSTQNNQKKVLAKTLISLPPQEATNSSKPQPTYEELEEEEQEDQFDLTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEARLLWANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVIRFEKEKSKDFKNHVIKYLETLLYSQQQLAKYWEAFLPEAKAIS

Physical form

Solution in phosphate buffered saline, pH 7.4

NCBI accession no.BC000357.1
clonepolyclonal
application(s)western blot: 1 µg/mL
application(s)immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
application(s)indirect immunofluorescence: suitable
shipped indry ice
antibody formpurified immunoglobulin
mol wtantigen ~57.42 kDa
storage temp.−20°C
Quality Level100
antibody product typeprimary antibodies
Gene Informationhuman ... SNX1(6642)
UniProt accession no.Q13596
conjugateunconjugated
biological sourcemouse
species reactivityhuman
formbuffered aqueous solution