SAB1405885-50UG Display Image

Anti-GNS antibody produced in mouse, purified immunoglobulin, buffered aqueous solution

Code: SAB1405885-50UG D2-231

General description

The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. De...

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£371.00 50UG
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General description

The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome. (provided by RefSeq)

Immunogen

GNS (NP_002067.1, 1 a.a. ~ 552 a.a) full-length human protein.SequenceMRLLPLAPGRLRRGSPRHLPSCSPALLLLVLGGCLGVFGVAAGTRRPNVVLLLTDDQDEVLGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSSKSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLEHVPLGWSYWYALEKNSKYYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNFEPFFMMIATPAPHSPWTAAPQYQKAFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLSVDDLVEKLVKRLEFTGELNNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLVANIDLGPTILDIAGYDLNKTQMDGMSLLPILRGASNLTWRSDVLVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTMSALWNLQYCEFDDQEVFVEVYNLTADPDQITNIAKTIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGYRFDPRLMFSNRGSVRTRRFSKHLL

Physical form

Solution in phosphate buffered saline, pH 7.4

clonepolyclonal
UniProt accession no.P15586
application(s)western blot: 1 µg/mL
shipped indry ice
antibody formpurified immunoglobulin
storage temp.−20°C
Quality Level100
antibody product typeprimary antibodies
conjugateunconjugated
Gene Informationhuman ... GNS(2799)
biological sourcemouse
mol wtantigen ~62.1 kDa
species reactivityhuman
NCBI accession no.NM_002076.2
formbuffered aqueous solution