SAB1300739-100UG Display Image

Anti-BIRC6 (N-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution

Code: SAB1300739-100UG D2-231

General description

BIRC6 is a member of a family of proteins that inhibit apoptosis, likely through interference with activation of ICE-like proteases. BIRC6, which contains...


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Your Price
£362.00 100UG

General description

BIRC6 is a member of a family of proteins that inhibit apoptosis, likely through interference with activation of ICE-like proteases. BIRC6, which contains a single BIR domain and a ubiquitin-conjugating enzyme domain, is expressed in four of six brain cancers (gliomas), and one of five ovarian cancers in a variety of human cancer cell lines. Brain cancer cell lines that overexpress BIRC6 demonstrate multi-drug resistance BIRC6 may protect cancer cells from undergoing apoptosis and participate in tumorigenesis and drug resistance.

Immunogen

BIRC6 (BIR6_HUMAN, 27-62)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human BIRC6.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

antibody formIgG fraction of antiserum
antibody product typeprimary antibodies
biological sourcerabbit
clonepolyclonal
conjugateunconjugated
formbuffered aqueous solution
Gene Informationhuman ... BIRC6(57448)
NCBI accession no.NP_057336
Quality Level100
shipped indry ice
species reactivityhuman
storage temp.−20°C
technique(s)immunohistochemistry: 1:50-1:100, indirect ELISA: 1:1000
UniProt accession no.Q9NR09
Quantity
Est. Dispatch/Availability