The Dead-Cert® technology has three components:


  • A proprietary solid phase that can selectively bind to dead and dying cells
  • Magnetic nanoparticles onto which the solid phase is coupled
  • A simple magnet

The coated nanoparticles attach to dead cells and debris and are then gently
separated from the viable cell population when a magnetic field is applied

Dead-Cert

Features & Benefits

  • Superior dead cell separation via small, super-paramagnetic Dead-Cert® nanoparticles - enables efficient and selective binding to non-viable cells and debris, using a simple magnet.
  • Specific separation - remove all inhibitory dead or dying cells in a single separation.
  • Simple and minimally invasive - gentle, non-toxic and non-cell clumping. A straight-forward process to ensure good cell viability, and improved growth rate, function and productivity of cells.
  • Cost-efficient - allows large savings in time, labour and resources with significant reduction in the cost of bioproduction and cell banking processes.
  • Reliable - process eliminates all dead cells and debris unlike low speed centrifugation
  • Flexible - scalable technology that can be used with various media and adapted to different platforms
  • Versatile application - applicable to most cell culture research and commercial biomanufacturing processes including antibody production as well as various downstream molecular biology analyses (RNA, DNA & Protein)
  • Complete kits available – nothing additional to buy
  • Full technical support, advice and custom services available - simplify and speed-up your research

Applications

  • Apoptosis research and/or cell viability assays
  • Antibody production/ biomanufacturing to increase the yield of cell-derived products; antibodies are generated in much higher quantities following removal of non-viable cells  
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  • Cryopreservation- reviving and expanding valuable cells such as T-cells, Stem cells or hybridoma cells following frozen storage and transport
  • Flow Cytometry – cleaner cell preparations for analysis and sorting; improves sensitivity
  • Enhancing the sensitivity of cell-based assays or drug screening assays ( e.g. chemotaxis, proliferation)
  • Stem cell and cancer research to improve culture and storage of cells
  • Improving transfection efficiency via production of stable high viability cell lines
  • Freshly isolated primary cells
  • Preparation of cells for biochemical analysis of DNA, RNA and protein
  • Improving drug screening through rapid removal of dead cells